Venuloside A( —— )

Catalog No. M37862 CAS No. 1609278-97-8

Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Venuloside A
Note

Research use only, not for human use.
Brief Description

Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer.
Description

Venuloside A is a potent inhibitor of LAT3. Venuloside A inhibits the leucine uptake in LNCaP prostate cancer cells with an IC50 of 8.12 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

transporter
Research Area

——
Indication

——

Chemical Information

CAS Number

1609278-97-8
Formula Weight

424.53
Molecular Formula

C23H36O7
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C(C)(C)[C@@H]1CCC(C)=CC1)[C@H]2[C@H](OC(C)=O)[C@@H](OC(C=C(C)C)=O)[C@@H](O)[C@@H](C)O2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wang Q, et al. Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth. ACS Chem Biol. 2014 Jun 20;9(6):1369-76.?

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